Rome has much to offer the intrepid traveller, whether you're seeking archaeological wonders, amazing shopping deals, or a romantic adventure. Depending on your itinerary (especially if you want to include all of the above on your trip), you would decide on the best area of Rome to book your accommodations. After all, you certainly don't want to be trekking around town all day and then have to travel for an hour to get back "home."
That said, if you do plan on changing hotels (or other accommodation) during your trip, be sure to book (and confirm) your hotel well in advance since these tend to be expensive but heavily booked. Hotel prices tend to be cheaper outside of Rome's central area, but this also makes travelling to sites of interest less convenient. However, a budget traveller or backpacker may not be deterred by this arrangement.
The Colosseum and Roman Forum are usually high on the itinerary list for travellers to Rome. A metro station and the Stazione Termini are located nearby, making it easier to travel to the area from other parts of the city. The neighbourhood also has a number of hotels for the convenience of those who wish to explore the area over a few days.
Romantics should head out to the Centro Storico on the Campo Marzo, which was used for military exercises by ancient Rome. Located at the centre of Rome, it features numerous winding medieval streets, piazzas, and fountains. The area also hosts numerous restaurants and bars. Piazza Navona and Campo dei' Fiori tend to be busy areas that are generally filled with tourists and locals. Other streets are more laid back with less activity. The charm of the area makes it a strong favourite among lovers of all ages. The area is most easily reached by buses and taxis from the Stazione Termini.
The ancient Via del Corso is often compared to London's Oxford Street and is a shopaholic's dream. From there up to the Spanish Steps of the Piazza di Spagna, shoppers will find an eclectic, cosmopolitan atmosphere among the narrow streets, charming cafes, and exclusive boutiques. In the vicinity of the Spanish Steps, you'll find the park of the Villa Borghese, the Piazza del Popolo, the Fontana di Trevi, and Via Margutta, which is a splendid artist's lane. Several restaurants and bars in the area are available to enhance your European experience.